Lawrence J Bonassar Selected Research

lubricin

1/2020	Effect of Lubricin Mimetics on the Inhibition of Osteoarthritis in a Rat Anterior Cruciate Ligament Transection Model.
1/2019	Boundary mode lubrication of articular cartilage with a biomimetic diblock copolymer.
1/2016	Galectin-3 Binds to Lubricin and Reinforces the Lubricating Boundary Layer of Articular Cartilage.
3/2009	Prevention of cartilage degeneration in a rat model of osteoarthritis by intraarticular treatment with recombinant lubricin.
3/2007	Binding and localization of recombinant lubricin to articular cartilage surfaces.

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Lawrence J Bonassar Research Topics

Disease

18	Osteoarthritis 04/2022 - 03/2007
10	Intervertebral Disc Degeneration 01/2022 - 12/2010
7	Arthritis (Polyarthritis) 11/2020 - 03/2009
5	Neoplasms (Cancer) 05/2019 - 10/2003
3	Wounds and Injuries (Trauma) 01/2020 - 01/2017
2	Hypertrophy 10/2017 - 03/2016
2	Fibrosis (Cirrhosis) 01/2017 - 12/2013
2	Foreign Bodies (Foreign Body) 12/2013 - 05/2006
1	Hyperglycemia 03/2022
1	Cartilage Diseases (Cartilage Disease) 02/2022
1	Sclerosis 01/2020
1	Inflammation (Inflammations) 01/2020
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2020
1	Temporomandibular Joint Disorders (Temporomandibular Joint Disorder) 12/2019
1	Breast Neoplasms (Breast Cancer) 05/2019
1	Radiculopathy (Radiculopathy, Cervical) 09/2018
1	Pain (Aches) 01/2018
1	Congenital Abnormalities (Deformity) 01/2018
1	Hypoxia (Hypoxemia) 10/2017
1	Intervertebral Disc Displacement (Herniated Disc) 06/2017
1	Neoplasm Metastasis (Metastasis) 01/2017
1	Athletic Injuries (Sports Injuries) 01/2017
1	Acquired Immunodeficiency Syndrome (AIDS) 01/2017
1	Ankle Injuries (Ankle Injury) 01/2017
1	Back Pain (Backache) 08/2016
1	Joint Diseases (Joint Disease) 03/2007
1	Tympanic Membrane Perforation 05/2006
1	Necrosis 03/2004
1	Osteopetrosis 01/2004
1	Bone Resorption 01/2004
1	Aneuploidy (Aneuploid) 10/2003
1	Tetraploidy 10/2003

Drug/Important Bio-Agent (IBA)

8	CollagenIBA 03/2022 - 10/2015
5	lubricinIBA 01/2020 - 03/2007
4	Hyaluronic Acid (Hyaluronan)IBA 04/2022 - 01/2018
4	Biological ProductsIBA 01/2022 - 01/2017
3	ViscosupplementsIBA 11/2020 - 01/2018
3	Proteins (Proteins, Gene)FDA Link 01/2020 - 03/2009
3	PolymersIBA 01/2019 - 05/2006
2	Dichlorodiphenyldichloroethane (DDD)IBA 04/2021 - 08/2016
2	LubricantsIBA 01/2018 - 01/2015
2	HydrogelsIBA 10/2017 - 01/2017
2	AlginatesIBA 01/2017 - 05/2006
1	Aggrecans (Aggrecan)IBA 02/2022
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2022
1	Indicators and Reagents (Reagents)IBA 01/2021
1	Proteoglycans (Proteoglycan)IBA 01/2021
1	GlycosaminoglycansIBA 01/2020
1	procollagen type II carboxy-terminal peptideIBA 01/2020
1	Collagen Type II (Type II Collagen)IBA 01/2020
1	IntegrinsIBA 01/2020
1	Dinoprostone (PGE2)FDA Link 01/2020
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2020
1	Blood Glucose (Blood Sugar)IBA 05/2019
1	salicylhydroxamic acid (SHAM)IBA 01/2019
1	SolutionsIBA 01/2018
1	Oxygen (Dioxygen)IBA 10/2017
1	poly-N-vinylcaprolactamIBA 10/2017
1	Pharmaceutical PreparationsIBA 01/2017
1	AntibodiesIBA 01/2017
1	Biocompatible Materials (Biomaterials)IBA 01/2017
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2017
1	Collagen Type XIBA 03/2016
1	Galectin 3 (LGALS3)IBA 01/2016
1	Collagen Type I (Type I Collagen)IBA 11/2010
1	Glycoproteins (Glycoprotein)IBA 03/2009
1	Prostaglandins AIBA 05/2006
1	Macrophage Colony-Stimulating FactorIBA 01/2004
1	DNA (Deoxyribonucleic Acid)IBA 10/2003

Therapy/Procedure

12	Therapeutics 01/2020 - 12/2013
3	Diskectomy (Discectomy) 11/2020 - 06/2017
2	Intra-Articular Injections 04/2022 - 12/2013
2	Injections 01/2022 - 01/2019
2	Punctures 03/2014 - 12/2010
2	Biological Therapy 10/2013 - 08/2011
1	Viscosupplementation 01/2019
1	Total Disc Replacement 09/2018
1	Sutures (Suture) 10/2017
1	Cell- and Tissue-Based Therapy (Cell Therapy) 08/2016
1	Herniorrhaphy 12/2013
1	Surgical Mesh 12/2013
1	Microspheres (Microsphere) 03/2004